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ECLS can be a life-saver for ARDS patients

Despite advances in treatment options, mortality and morbidity in patients with acute respiratory distress syndrome (ARDS) remain high. Extracorporeal membrane oxygenation (ECMO) has emerged as a promising intervention. [1] Improvements in technology have made ECMO safer and easier to use, allowing for the potential of more patients with ARDS receiving this therapy.

Why ECMO for ARDS?

In the setting of severe ARDS, oxygen delivery can become insufficient to satisfy the body's demand. The main purpose of respiratory ECMO is to maintain oxygenation of the organs. It can stabilize gas exchange and minimize hemodynamic compromise, thus preventing further organ damage.[2]

ECMO is not a treatment for the underlying cause of ARDS. It allows time for investigation and to develop a specific treatment strategy targeted at the underlying disease.[2]

Getinge Cardiohelp

What is ECMO?

ECMO refers to a circuit that directly oxygenates and removes carbon dioxide from blood through an extracorporeal gas exchange device, commonly referred to as a membrane oxygenator. Two catheters or cannulas are inserted at the initiation of ECMO with their drainage and reinfusion ports located in central vessels. Deoxygenated blood is drained from the body by an external pump, it passes through the membrane oxygenator and is then reinfused back into the patient. Respiratory or venovenous ECMO which provides only gas exchange support.

About extracorporeal membrane oxygenation (ECMO)

The use of extracorporeal membrane oxygenation (ECMO) for the treatment of ARDS was introduced in the early 70‘s with the aim of guaranteeing a protective ventilation and minimizing the risk for the ventilator induced lung injury [3]. It works similar to an artificial lung providing adequate blood CO removal and oxygenation thus minimizing mechanical ventilation. [4] [5]

Getinge Cardiohelp helicopter transport

Transport on ECMO

Because ECMO is considered an advanced therapy. It requires training in the necessary techniques and the formation of a network of hospitals to manage these patients is essential. In cases of severe ARDS, ECMO transport may be safer than transport on ventilation when transferring to an ECMO management center is necessary. [6]

Learn more about transport on ECMO

Related Products

Extracorporeal Life Support

Our broad, high-end product portfolio for short-term or prolonged extracorporeal life support (ECLS) or extracorporeal membrane oxygenation (ECMO) includes a choice of devices and consumables to provide individual and sufficient extracorporeal heart and/or lung support, such as centrifugal pumps, oxygenators, heater units, tubing sets, and catheters and cannulae.

Read more about Extracorporeal Life Support

Cardiohelp System

The small and lightweight heart-lung support system.

Read more about Cardiohelp System

Surgical Perfusion

Advanced surgical perfusion components were used successfully for millions of cardiopulmonary bypass procedures worldwide each year. The Getinge heart-lung perfusion system is part of an established, comprehensive cardiac surgery suite portfolio, ensuring compatible solutions.

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All references

  1. 1. Ventetuolo CE, Muratore CS. Extracorporeal life support in critically ill adults. Am J Respir Crit Care Med. 2014;190(5):497–508.

  2. 2. Extracorporeal membrane oxygenation for acute respiratory distress syndrome, Journal of Intensive Care, 2015, DOI: 10.1186/s40560-015-0082-7

  3. 3. Fan E, Brodie D, Slutsky AS. Acute Respi­ratory Distress Syndrome: Advances in Diagnosis and Treatment. JAMA. 2018 Feb 20;319(7):698-710.

  4. 4. Michele Umbrello, Paolo Formenti, Luca Bolgiaghi, and Davide Chiumello | Current Concepts of ARDS: A Narrative Review. | Int J Mol Sci. 2016 Dec 29;18(1). pii: E64. doi: 10.3390/ijms18010064

  5. 5. Steven A. Conrad , L. Mikael Broman , Fabio S. Taccone , Roberto Lorusso , Maximilian V. Malfertheiner , Federico Pappalardo , Matteo Di Nardo , Mirko Belliato , Lorenzo Grazioli , Ryan P. Barbaro , D. Michael McMullan , Vincent Pellegrino , Daniel Brodie , Melania M. Bembea , Eddy Fan , Malaika Mendonca , Rodrigo Diaz , and Robert H. Bartlett | The Extracorporeal Life Support Organization Maastricht Treaty for Nomenclature in Extracorporeal Life Support. A Position Paper of the Extracorporeal Life Support Organization | All ajrccm Issues Vol. 198, No. 4 | Aug 15, 2018

  6. 6. Toshiyuki Aokage, Kenneth Palmér, Shingo Ichiba and Shinhiro Takeda | Extracorporeal membrane oxygenation for acute respiratory distress syndrome | Journal of Intensive Care20153:17