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Cardiovascular disease (CVD) is the number one cause of death worldwide with an estimated 17.5 million deaths each year, representing 30 % of all deaths.[1]

Cardiohelp System

Do you know the different ECLS/ECMO therapy options?

Many CVD patients experience cardiogenic shock, a frequent consequence of a heart attack, because the heart muscle is not adequately supplied with oxygen. Other conditions that can lead to failure of the heart and/or lungs include acute respiratory distress syndrome (ARDS), severe influenza (e.g., H1N1), septic shock and pulmonary embolism. Patients with serious cardiac and/or pulmonary compromise require immediate stabilization and perhaps inter-hospital transfer.

Extracorporeal life support (ECLS), or extracorporeal membrane oxygenation (ECMO), has become a standard therapy option to stabilize blood circulation and/or respiratory functions of affected patients. [2]

Cardiohelp System

ECLS therapy to prevent organ damage

ECLS or ECMO can be used to temporarily support heart and/or lung function (i.e. either partial or total support) during cardiopulmonary failure. [3] Veno-arterial life support is used with patients whose hearts are not adequately supporting their circulation, which may occur with a myocardial infarction. Veno-venous life support provides respiratory assistance for lung disorders, and is primarily used when the heart is still able to pump blood through the circulatory system without any additional support. [4]

Tree lung visual

Reduction of blood CO₂

Facilitating protective ventilation strategies, even in severe cases of acute respiratory failure

The veno-venous use of the Cardiohelp System ensures an effective oxygen supply and/or the reduction of blood CO2 level in intensive care patients suffering from ARDS, sepsis or other indications associated with acute respiratory failure. [4] [5]

ARDS

Did you know that ECLS could be a life saver for ARDS patients?

Severe acute respiratory distress syndrome (ARDS) continues to have still has a high mortality rate.[7] Extracorporeal life support (ECLS) can be a good therapy option when standard therapies fail.[8] The use of ECLS for adult ARDS has increased over the last decade. More and more specialized centers use perform ECLS today, and there are many reports available that confirm that ECLS therapies deliver improved outcomes for adult ARDS patients. [9]

With critically ill or injured patients, there’s no time for delay. That’s why Getinge has long been committed to advancing ECLS technology. 

The Cardiohelp System is a small and lightweight heart-lung support system.

Although extracorporeal life support provided by the Cardiohelp System is not a therapy itself, it acts as a bridge for recovery or transplantation. This gives caregivers more time to optimize the patient’s therapy while easing the body’s workload.

Alle referanser

  1. World Health Organization, Global status report on non-communicable diseases 2014.

  2. Butt W, MacLaren G. (2016) Extracorporeal membrane oxygenation 2016: an update; F1000Res. 2016 Apr 26;5. pii: F1000 Faculty Rev-750. doi: 10.12688/f1000research.8320.1

  3. Tran BG, De La Cruz K, Grant S, Meltzer J, Benharash P, Dave R, Ardehali A, Shemin R, Depasquale E, Nsair A.; Temporary Venoarterial Extracorporeal Membrane Oxygenation: Ten-Year Experience at a Cardiac Transplant Center; 2016; J Intensive Care Med. 2016 Jun 14. pii: 0885066616654451.

  4. ELSO Guidelines for Cardiopulmonary Extracorporeal Life Support; Extracorporeal Life Support Organization, Version 1.3 November 2013; Ann Arbor, MI, USA;

  5. Michele Umbrello, Paolo Formenti, Luca Bolgiaghi, and Davide Chiumello | Current Concepts of ARDS: A Narrative Review. | Int J Mol Sci. 2016 Dec 29;18(1). pii: E64. doi: 10.3390/ijms18010064

  6. Steven A. Conrad , L. Mikael Broman , Fabio S. Taccone , Roberto Lorusso , Maximilian V. Malfertheiner , Federico Pappalardo , Matteo Di Nardo , Mirko Belliato , Lorenzo Grazioli , Ryan P. Barbaro , D. Michael McMullan , Vincent Pellegrino , Daniel Brodie , Melania M. Bembea , Eddy Fan , Malaika Mendonca , Rodrigo Diaz , and Robert H. Bartlett | The Extracorporeal Life Support Organization Maastricht Treaty for Nomenclature in Extracorporeal Life Support. A Position Paper of the Extracorporeal Life Support Organization | All ajrccm Issues Vol. 198, No. 4 | Aug 15, 2018

  7. Ventetuolo CE, Muratore CS. Extracorporeal life support in critically ill adults. Am J Respir Crit Care Med. 2014;190(5):497–508.

  8. Bellani G, Laffey JG, Pham T, et al. LUNG SAFE Investigators; ESICM Trials Group. Epidemiology, Patterns of Care, and Mor­tality for Patients With Acute Respiratory Distress Syndrome in Intensive Care Units in 50 Countries. JAMA. 2016 Feb 23;315(8):788- 800.

  9. Toshiyuki Aokage, Kenneth Palmér, Shingo Ichiba and Shinhiro Takeda; Extracorporeal membrane oxygenation for acute respiratory distress syndrome; Journal of Intensive Care20153:17