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Heartstring III Proximal Seal System

Heartstring III brings proximal anastomotic technology into the future. A hemostatic seal enables surgeons to eliminate partial occlusion clamps and minimize aortic manipulation during proximal anastomosis that can lead to complications.[1]

When it comes to a stroke, leave nothing to chance

The Heartstring III proximal anastomotic seal technology allows for clampless hemostasis during proximal anastomoses when performing CABG procedures. It allows hand suturing without using either the cross clamp or the side-biting clamp. Minimizing the manipulation of the ascending aorta reduces the risk of neurologic complications.[1]


Minimizing the manipulation of the ascending aorta reduces the risk of neurologic complications. In patients with minimal aortic diseases the cerebral emboli number is significantly reduced when the Heartstring III device is used.[1]


Allows use of the surgeon’s own hand sewn and angled take-off technique for optimal anastomotic quality and procedural flexibility.


The loading device and aortic cutter make Heartstring III seal placement fast and easy.

Heartstring III Proximal Seal System consists of 3 components

Aortic Cutter

Aortic Cutter

The Aortic Cutter is easy to use, and makes a single, clean hole in the aorta.

Seal loader and delivery device

Loader and Delivery Device

The innovative loading device makes the Heartstring III proximal seal placement fast and easy.

Aortic Cutter


The Heartstring III Proximal Seal is an innovative advance in proximal anastomotic seal technology.

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  1. 1. El Zayat H, Puskas JD, Hwang S, Thourani VH, Lattouf OM, Kilgo P, Halkos ME.Avoiding the clamp during off-pump coronary artery bypass reduces cerebral embolic events: results of a prospective randomized trial. Interact Cardiovasc Thorac Surg. 2012 Jan;14(1):12-6

  2. 2. Puskas J, Martin J, Cheng D, et al. ISMICS Consensus Conference and Statements of Randomized Controlled Trials of Off-Pump versus Conventional Coronary Artery Bypass Surgery. Innovations. 2015;10:219-229.