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GEV Steam/Air Mixture Sterilizers

Rapid and versatile terminal sterilization for packaged pharmaceuticals

Getinge GEV sterilizers are designed for sterilizing pharmaceutical products that must be dry and ready for further handling immediately after the cooling phase.

GEV Steam/Air Mixture Sterilizer with biopharma at customer site with a man working next to it
GEV Sterilizer with a man next to it that touches the display for monitoring
GEV Steam/Air Mixture Sterilizer loading biopharma at customer site

Safe, efficient and cGMP compliant terminal sterilization processes

  • Flexible process design
  • Effective process control
  • Efficient throughput
  • Automated loading solutions

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Optimizing process design

The correct packaging and drug delivery systems play an important role in easing drug administration and improving patient safety. Yet the wide variety of products and packaging styles present significant challenges for the biopharmaceutical industry. Terminal sterilization puts stringent demands on efficient sterilization while protecting both product and packaging.

Getinge supports you by defining optimal process parameters for your specific product and packaging. GEV Steam/Air mixture sterilizers offer versatile sterilization processes to achieve correct temperature and pressure throughout the process cycle.

GEV terminal sterilization

Control over temperature and pressure

Temperature and pressure within the chamber must be carefully controlled and evenly distributed to prevent packaging deformation during sterilization.

Getinge GEV Steam/Air Mixture Sterilizers use sterile compressed air to apply support pressure to balance the environment with the internal load pressure, meeting each load’s requirements for heating and cooling rates. Pressure and temperature sensors within the chamber control and adjust when necessary. A fan and ducting create a circulation pattern and maintain a homogeneous environment when it comes to temperature and pressure.

Rack design supports efficacy

Rack and shelf design play a key role in process efficacy and product protection. They must allow adequate and uniform flow of sterilizing media while supporting the product to prevent damage or deformation. Getinge supports you with wide variety of shelving systems, and offers test and prototyping services to assist in the design of shelving for your specific process requirements.

Optimized throughput

Pre-heating for dry loads

While steam-heating is energy efficient, the resulting condensation can be problematic for downstream processing. The drying result can be improved by pre-heating with dry air. In this process, the circulating air is heated, which then heats the load prior to steam injection. When steam is injected, less energy is required to raise the load to sterilization temperature. Less steam means less condensate, resulting in a drier load.

Rapid cooling

Getinge uses bundled heat exchangers placed in the path of the circulating steam/air mix to rapidly and efficiently cool the sterilized goods. As the product temperature decreases, the pressure is reduced; this maintains balance with the load’s internal pressure to prevent compression or distortion of the container. As result, the products emerge sterile, cool, dry, and ready for further downstream processing.

Sterilizers for all capacity needs

The GEV Steam/Air Mixture Sterilizers offer a wide range of chamber sizes and configurations ranging from 0,36m3 to 16,3 m3 to meet your capacity needs. The range also offers single or double door (pass through) models, and a service area on either side of the chamber. The sterilizers can be mounted in a cabinet, recessed between two walls, or recessed in a wall with a surrounding cabinet.

The modular, automated load handling solution for Getinge GEV sterilizers

The Getinge Roller Conveyor System (GRCS)

The GRCS ensures safe, continuous pharmaceutical production by optimizing load-handling performance throughout the terminal sterilization cycle.

  • Optimizes production efficiency, uptime, and throughput
  • Protects the GEV terminal sterilizer from loading and unloading risks
  • Eliminates risk of human injury
  • Prevents heavy or unwieldy loads being dropped
  • Support traceability for quality assurance and compliance
  • Compliant with applicable safety standards
  • Easy-to-use operations
  • Modular design makes it suitable for all production environments
  • Harmonious integration with GEV sterilizers as part of a single-vendor solution


The GRCS is based around a motorized roller carriageway onto which batches can be placed before safe transfer into the GEV sterilization chamber. This makes the process of placing batches onto the GRCS independent of the process of feeding batches into the sterilizer.


Once the terminal sterilization cycle is complete, a corresponding GRCS carriageway at the opposite end of the sterilizer can be utilized to support the unloading process. Each GRCS carriageway can be configured to connect with existing upstream and downstream conveyor systems where required.


The automated features of the GRCS include sensors and scanners that are seamlessly integrated with the operation of the GEV sterilizer as part of a complete Getinge solution. This allows full traceability of loading racks and enables autonomous chamber loading and start of sterilization process.

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