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Informed anesthetic agent dosing

To facilitate decision-making when planning and dosing anesthesia agents, we created MAC Brain. Using mathematical models and data-driven algorithms, MAC Brain visualizes the difference in agent concentration between the lung and the brain - providing the clinician with valuable information that supports informed dosing decisions.[1] 

MAC Brain illustration



A monitoring tool for general anesthesia

Due to pharmacokinetics, there is a time delay in agent concentration between the end-tidal MAC and the target organ.

MAC Brain visualizes the difference to support better dosing and planning of agent delivery.

A unique feature on all our Flow Family anesthesia machines.

How MAC Brain works

The image shows the interface of Flow Family anesthesia machines.
The end-tidal MAC and MAC brain are found in the lower left corner of the screen (marked with a green frame). The interface snapshot was taken during induction, when the difference between the two values is often the highest.

MAC Brain is visualized on screen using an algorithm based on basic research and pharmacokinetic models. The option is included in the 4.7 software and is easily brought forward and removed from the menu when needed.

MAC Brain Flow Family anesthesia

More unique innovations for our anesthesia machines

With our flow anesthesia technology you can easily ensure the perfect flow for each patient, finetuning anaesthesia delivery in real time, breath by breath.

AGC Anesthesia Flow

Automatic Gas Control

O2Guard Anesthesia Flow


Lung recruitment Flow Anesthesia

Lung recruitment

Ventilation Anesthesia Flow

Ventilation performance


The products, availability of the Flow Family anesthesia systems and SW version may be pending regulatory approvals to be marketed in your country. Contact your Getinge representative for more information. The assertions stated by the physician are strictly those of the physician and do not necessarily reflect the views of Getinge.
Legal Manufacturer · Maquet Critical Care AB · Röntgenvägen 2 SE-171 54 Solna · Sweden · +46 (0)10 335 73 00

  1. 1. Drews FA, Syroid N, Agutter J, Strayer DL, Westenskow DR. Drug delivery as control task: improving performance in common anesthetic task. Hum Factors 2006;48:85–94.

  2. 2. ECRI. The MAC Brain feature on Getinge anesthesia units: ECRI's view. Device Evaluation 2022 Jan5.

  3. 3. Internal report EVU-197031 - 01 - Flow 4.7 Enhanced Post Market Surveillance Report 2019

  4. 4. Internal report EVU-194160 - User evaluation EPMS Flow 4.7 2019