Visualizing agent concentration in the target organ
Informed anesthetic agent dosing
To facilitate decision-making when planning and dosing anesthesia agents, we created MAC Brain. Using mathematical models and data-driven algorithms, MAC Brain visualizes the difference in agent concentration between the lung and the brain - providing the clinician with valuable information that supports informed dosing decisions.
A monitoring tool for general anesthesia
Due to pharmacokinetics, there is a time delay in agent concentration between the end-tidal MAC and the target organ.
MAC Brain visualizes the difference to support better dosing and planning of agent delivery.
A unique feature on all our Flow Family anesthesia machines.
How MAC Brain works
The image shows the interface of Flow Family anesthesia machines.
The end-tidal MAC and MAC brain are found in the lower left corner of the screen (marked with a green frame). The interface snapshot was taken during induction, when the difference between the two values is often the highest.
MAC Brain is visualized on screen using an algorithm based on basic research and pharmacokinetic models. The option is included in the 4.7 software and is easily brought forward and removed from the menu when needed.
Potential use areas for MAC Brain
Discussions with early adopters of MAC Brain has identified the following uses:
- Provides more information when monitoring the depth of anesthesia, especially during induction and emergence.
- Provides additional information when the patient may be at risk of over or underdosing.
The chart illustrates what early adopters answered when asked about the benefits they experienced with MAC Brain during surgery. 
More unique innovations for our anesthesia machines
With our flow anesthesia technology you can easily ensure the perfect flow for each patient, finetuning anaesthesia delivery in real time, breath by breath.
The products, availability of the Flow Family anesthesia systems and SW version may be pending regulatory approvals to be marketed in your country. Contact your Getinge representative for more information. The assertions stated by the physician are strictly those of the physician and do not necessarily reflect the views of Getinge.
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