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Pendotech Bioprocessing Sensors

Real-time in-line monitoring for bioprocess control. 

Distributor Line: As part of HPNE’s partner portfolio, this product extends our ability to deliver complete and reliable bioprocessing solutions under Getinge.

The PendoTECH In-Line Conductivity Sensor, used for real-time monitoring of solution concentration in bioprocess systems.
The PendoTECH Conductivity Monitor displays real-time measurement and logging data via a digital screen.
The compact, PendoTECH Turbidity Photometer, showing the main body and the labeled sections.
The PendoTECH Single-Use In-Line UV Absorbance Photometer can detect protein concentration at 280nm using a single-use flow path.

Simplifying control in complex workflows

Pendotech offers a comprehensive suite of in-line, single-use monitoring solutions designed to give you total confidence in your bioprocessing workflows. By integrating high-precision Single-Use Pressure, Temperature, and Conductivity sensors with the reliable analytical power of the PressureMAT Sensor Monitor and Conductivity Monitor, this system provides a clear, real-time window into your process stability. To ensure complete fluid quality, the Turbidity Photometer and Single-Use In-line UV Absorbance Photometer provide non-invasive optical data, allowing you to monitor protein concentration and fluid clarity without the need for manual sampling or the risk of contamination. These tools work together to simplify your path from discovery to commercial-scale production, reducing the burden of cleaning and validation so you can focus on what’s important: your product.

Applications:

  • Chromatography & Fractionation: Correlate UV Absorbance with Conductivity shifts to automate fraction collection and improve purity.
  • Filtration & Integrity: Use the PressureMAT and Turbidity Photometer to detect breakthrough early and protect high-value membranes.
  • Buffer & Media Preparation: Ensure formulations meet exact specifications with temperature-compensated Conductivity and Temperature monitoring.
  • TFF / Cross-Flow Control: Optimize flux rates and concentration stability by tracking feed, retentate, and permeate pressures in real-time.
  • Closed-Loop Integrity: Maintain sterility with non-invasive sensors that eliminate the need for manual sampling and post-run validation.

Related products

Related products

Pressure monitoring

  • Monitor feed, retentate, and permeate pressures simultaneously
  • Identify system excursions instantly with automated threshold alarms
  • Connect seamlessly to disposable fluid paths via Hose Barb or Triclamp fittings

Temperature precision

  • Capture high-accuracy thermal data without breaking the sterile barrier
  • Maintain product stability by tracking temperature in real-time
  • Integrate pre-calibrated sensors into any single-use manifold

Conductivity analysis

  • Measure salt concentrations accurately across a wide dynamic range
  • Eliminate cross-contamination risks with single-use conductivity cells
  • Compensate for thermal shifts automatically to ensure data integrity

 

UV Absorbance

  • Track protein concentrations continuously at 280nm without manual sampling
  • Optimize fraction collection by identifying elution peaks as they occur
  • Utilize compact, in-line flow cells to minimize hold-up volume

Turbidity detection

  • Detect particle breakthrough or precipitates at 880nm (NIR)
  • Monitor fluid clarity to protect downstream filters and membranes
  • View results on a local display or transmit data to your central system

PressureMAT control

  • Consolidate up to four pressure channels into a single user interface
  • Trigger pump stops or valve switches based on real-time alarm inputs
  • Standardize your data logging with high-resolution digital outputs

Conductivity monitoring

  • Simplify your hardware setup with a dedicated, high-resolution monitor
  • View conductivity and temperature readings on one bright local display
  • Output 4-20mA signals for easy integration with your PLC or SCADA

 

System integration

  • Bridge the gap between individual sensors and your automated control system 
  • Reduce setup time with plug-and-play connections across all PendoTECH hardware
  • Eliminate cleaning and validation burdens with a 100% single-use sensor suite

Pressure & Temperature Sensors & Monitoring Systems

The PendoTECH Single-Use Pressure Sensor designed for accurate, non-intrusive pressure measurement in fluid systems.

The Single-Use Pressure Sensors and Single-Use Temperature Sensors are standard in the industry for monitoring single-use fluid paths. When paired with the Pressure / AT Sensor Monitor, they provide high-frequency data logging and support process control, system integrity, and safety interlocks for pumps and valves.

Specification Single-Use Pressure Sensor Single-Use Temperature Sensor
Operating Range -7 to 75 psi 32°F to 158°F
Accuracy ±2% of reading ±0.2°F (at 98.6°F)
Repeatability ±0.05 psi ±0.1°F
Burst Pressure >150 psi >1005 psi
Max Fluid Temperature 140°F (at 30 psi) 158°F (steam)
Compliance USP Class VI / ADCF USP Class VI / ADCF

 

Specification Pressure / AT Sensor Monitor
Input Channels 1 to 4 sensor inputs
Accuracy ±1% Full Scale
Repeatability ±0.02% Full Scale
Max Ambient Temperature 122°F
Compliance CE Marked / RoHS

 

Conductivity Sensors & Monitoring Systems

The PendoTECH Conductivity Monitor displays real-time measurement and logging data via a digital screen.

The Single-Use Pressure Sensors and Single-Use Temperature Sensors are standard in the industry for monitoring single-use fluid paths. When paired with the Pressure / AT Sensor Monitor, they provide high-frequency data logging and support process control, system integrity, and safety interlocks for pumps and valves.

Specification Single-Use Conductivity Sensor
Measurement Range 0.1 to 200 mS/cm
Temperature Compensation Integrated thermistor
Repeatability ±0.05 mS/cm
Max Operating Pressure 75 psi at 77°F
Fitting Sizes 1/4", 1/2", 3/4", 1"

 

Specification Conductivity Transmitter / Monitor
Display Digital local display
Temperature Compensation Automatic (21°C / 69°F)
Accuracy ±0.1% of range
Output Signals 4–20 mA or 0–5 V
Mounting Options Panel mount or desktop

 

Optical Sensors: UV Absorbance * Turbidity

The PendoTECH Single-Use In-Line UV Absorbance Photometer can detect protein concentration at 280nm using a single-use flow path.

The Single-Use In-Line UV Absorbance Photometer and In-Line Turbidity Photometer provide real-time measurement of concentration and fluid clarity. The UV system utilizes a long-life LED source for stable protein detection, while the turbidity system uses NIR light to avoid interference from colored fluids, enabling reliable in-line monitoring without interrupting the process stream.

Specification Single-Use In-Line UV Absorbance Photometer In-Line Turbidity Photometer
Light Source 280 nm LED (solid state) 880 nm NIR LED
Measurement Range 0 to 3.0 AU 0 to 4000 NTU
Repeatability ±0.01 AU ±1% of full scale
Pathlength Options 0.04", 0.08", 0.19", 0.39" Supports 1/4" to 1" tubing
Max Fluid Temperature 122°F 122°F
Max Pressure 75 psi 75 psi
Compliance USP Class VI / NIST traceable USP Class VI / NIST traceable