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Closure Processing System (CPS)

Clean, sterile, and dry stoppers and closures delivered to the filling machine without breaking containment.

Getinge's Closure Processing System (CPS) provides an unbroken chain of sterility for efficient processing of all types of closures in conjunction with filling lines in pharmaceutical production.

Closure Processing System
Closure and stopper sterilization with a Closure processing system and autoclave

Unbroken chain of sterility

  • Efficient closure processing
  • Minimize manual handling and intermediate transfers
  • Complete process capabilities

Treatment unit

The MPV is connected to the treatment unit (WSSD) for complete processing of the closures within the vessel by washing, siliconizing, sterilizing, and drying.

Storage and transfer

Transport washed, sterilized, and siliconized (optional step) closures directly to the filling line for aseptic transfer, or store in the MPV until use.

Closure discharge

A lift-and-turn station (LTS) enables the MPV to dock with the filling machine and discharge its load of closures aseptically.

Illustration of closure processing system

Washing, rinsing, and siliconization

Closures in the MPV are subjected to the agitation of sterile filtered air passing through water to fluidize the load during the washing, rinsing and siliconizing (if required) steps. The combination of forceful airflow and constant water overflow moves the closures to ensure continuous removal of particles.

Bottle syringe vial

Adjustable process conditions

The process conditions can be adjusted to suit the particular closure being treated. The closures, vessel and piping system are steam-sterilized using a traditional vacuum steam sterilization process.

Closure processing solution illustration

Drying and cooling

The closures are dried using a combination of heated sterile air and vacuum drying, and are finally cooled using compressed air. Periodic air shocks prevent the closures from clumping. Drying parameters can be adjusted to meet levels required for lyophilized products.