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Applikon MiniBio

The Applikon MiniBio is a true scale down of the classic laboratory scale bioreactor. It has the same flexibility, which means that the Applikon MiniBio can be customized to fit the demands of any process. The small volume reduces media costs and maximizes usage of bench space.

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Your interest in bioreactor systems

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.  

Argentina

AP Biotech
Phone: +541142921611
Email: info@apbiotech.com.ar
URL: www.apbiotech.com.ar

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.  

Brazil

Sotelab
+55 (21) 3392-3563
www.sotelab.com.br

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Chile, Peru

AP Bioprocess
www.ap-bioprocess.com

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China

Applitech
Phone: +862034821111
Email: biotech@applitechpharma.com 
URL: www.applitechpharma.com

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Colombia

Intek Group
Phone: +57 316 3550400 - 749 8437
Email: contacto@intekgroup.com.co
URL: www.intekgroup.com.co

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Czech Republic

Vekamaf
Phone: +420 284 690 881
URL: www.vekamaf.cz

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Denmark

Holm & Halby
Phone: +454326 9400
Email: info@holm-halby.dk
URL: www.holm-halby.dk

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Estonia

Bio Techa
Phone: +372 6597101
Email: info@biotecha.ee
URL: www.biotecha.lt

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Hungary

Holimex
Phone: +36 1 391 4400
URL: www.holimex.hu

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

India

Spinco Biotech Pvt. Ltd.
Phone: +91 44 45678900
Email: info@spincotech.com
URL: www.spincotech.com

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Indonesia

PT Arico Sainsindo Nusantara
Phone: +62-21 580 6342 / 3
Email: arico@dnet.net.id
URL: www.ptarico.com

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.  

Ireland

Asistec
Phone: +353(0)1286 8796
Email: info@asistec.ie
URL: www.asistec.ie

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Israel

Medent Group
Phone: +97286237984
Email: info@medent.co.il
URL: medent.co.il

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Italy

Steroglass
Phone: +39 075 609091
Email: info@steroglass.it 
URL: www.steroglass.it

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Japan

Sanyo Trading Co., LTD
Phone: +81-3-3518-1196
URL: www.sanyo-trading.co.jp

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Lithuania

Bio Techa
Phone: +370 5 237 60 07
Email: info@biotecha.lt
URL: www.biotecha.lt

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Norway

Bio Nordica
Phone: 23 03 58 00
Email: info@bionordika.no
URL: bionordika.no

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Poland

Labo Baza
Phone: +4861 812 57 45
Email: biuro@labobaza.pl
URL: www.labobaza.pl

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Russia

Abtek
Phone: +7(495) 723-64-97
Email: abtek@abtek.ru
URL: abtek.ru

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Singapore

Zil Sci Pte. Ltd.
Phone: +65 6767 2929
Email: ENQUIRY@ZILSCI.COM
URL: www.zilsci.com

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Slovakia

Vekamaf
Phone: +421-2-52932891
URL: www.vekamaf.cz

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South Africa

Seperations
Phone: +27 11 919 1000
Email: info@separations.co.za
URL: separations.co.za

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South Korea

SeouLin Bioscience
Phone: +821670-5911
Email: support@seoulin.co.kr
URL: www.seoulin.co.kr

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Switzerland

Resea Biotec
Phone: +41 34 531 08 20
Email: office@reseabiotec.ch
URL: www.reseabiotec.ch

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Taiwan

Tseng Hsiang Life Science Ltd.
Phone: +862-27851156
Email: info@thco.com.tw
URL: www.thco.com.tw

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Meditop Co., Ltd

Holm & Halby
Phone: +662 9331133
Email: info@meditopthailand.com
URL: meditopthailand.com

We have a local distributor for this country. Feel free to reach out directly via below phone number, email or website for quickest response.

Turkey

Ant Teknik
Phone: +90 216 422 6700
Email: antteknik@antteknik.com 
URL: www.antteknik.com

Real Small... Real Bioreactors

  • Easy set up and operation
  • Little bench space required
  • Less medium used during cultivation
  • Generate more data in less time

The MiniBio is the perfect device for small-scale operations in the lab. It saves time, takes up less bench space, and generates more data while providing fully scalable results. In combination with our highly efficient BioSep cell separation device, you can convert your batch or fed-batch bioreactor into a small scale continuous bioprocessing system.

The configurable head plate of the bioreactor has Luer fittings that free up space for multiple additions, sensors and fittings and ready-to-go tubing assemblies for a quick start.

Microbial and cell cultures at small scale

Sometimes less leads to more.
The Applikon MiniBio requires less medium and bench space than regular laboratory-scale bioreactors. Scientists can easily run multiple experiments in parallel, generating more data at once to enable efficient scale-up.

Watch the video to view how the MiniBio can speed up your bioprocess.

Small size bioreactors

The compact design of the MiniBio allows the scientist to place multiple systems on the valuable bench space. Parallel processing has never been that easy. 

Generate scalable results

Running cultivations at small scale allows for quick access to more data. Scientists will have reliable data that simplifies scale-up to higher volumes.

Specifications

 

MiniBio 250

MiniBio 500

MiniBio 1000

Total volume (mL) 290 550 1250
Working volume (mL) 200 400 1000
Minimum working volume (mL) 50 100 200
Aspect ratio total volume 2.3 2.1 2.3
Aspect ratio working volume 1.6 1.5 1.9
Dimensions (dxh) 180 x 400 mm 195 x 400 mm 200 x 550 mm
Dimensions for autoclaving (dxh) 180 x 250 mm 195 x 250 mm 200 x 400 mm
Drive system Direct drive, lipsealed Direct drive, lipsealed Direct drive, lipsealed
Maximum stirrer speed (rpm) 50 - 2000 50 - 2000 50 - 1750
Maximum impeller tip speed (m/s) 2.3 2.9 3.5
Impellers Choice of Rushton and Marine
Gas sparger Porous sparger, open pipe sparger or jet sparger
Gas overlay Yes
Exhaust gas Electrically cooled exhaust gas condenser (evaporation <4% per day at 37°C @ 2vvm)
Sampling Fixed sample pipe with optional sampling system
Draining Height adjustable drain pipe
Additions 4 fixed inlet ports and optional micro liquid injectors
pH Measurement: 8 mm classic pH sensor
Control: via acid pump (variable speed pump) or CO2 gas
in combination with alkali pump (variable speed pump)
DO2 Measurement: LumiSens Optical DO2 sensor.
Control: via a combination of N2, Air, O2 (needle valve standard,
MFC optional) and agitation
Temperature Measurement: Pt-100 sensor in thermowell in topplate
Control: electrical cooling and heating jacket via bioreactor wall
Foam Measurement: Height adjustable conductivity based foam sensor
Control: anti-foam addition (variable speed pump)
Level Measurement: Height adjustable conductivity based level sensor
Control: variable speed pump for liquid addition or removal
Optional inlets Septum, chemostat tube, liquid entry system
Optional sensors Biomass, Optical Density, O2 and CO2 off gas, weight balance