- Overview
- Features
- Applications
Applikon SUB-Control
Controlling Single-use in Pilot & Production
- Fully configurable controller based on your requirements
- Turn-key package with Thermo Fisher HyPerforma S.U.B. and S.U.F.
- Variety of software platforms available for maximum connectivity
The SUB-Control is a controller designed to work with pilot and production scale single use bioprocessing systems. It can be integrated with the Thermo HyPerforma S.U.B. in the range of 50 to 2000L maximum working volume, or the Thermo HyPerforma S.U.F in 30L of 300L size or Pall or millipore Single use Bioreactors. The SUB-Control is equipped with the latest standard in pump, MFC and sensor technology. The SUB-Control comes in two versions. The SUB-Control ONE is based on the Applikon software platform which has the same advanced features as our bench top scale solutions such as the my-, ez-, ez2- and in-Control. The SUB-Control PLUS is based on PLC technology similar to our i-Control.
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Specifications
| Sensors | SUB One | SUB Plus |
| pH Sensor | Traditional electrochemical Single use sensor options, redundant options avaliable |
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| DO sensor | Traditional Polarographic Single use sensor options, redundant options avaliable |
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| Redox | Optional | |
| Temperature | Pt-100, Measurement Range: 0-150 °C accuracy 0,1°C | |
| Foam / level | Resistive based measurement | |
| Weight | Reactor load cells and balances | |
| Optional | Biomass (Capacitance or optical density), offgas measurements, pressure | |
| Additional I/O | Up to 8 Analog in and 4 Analog out | Configurable Up to 8 Digital In and 8 Digital out |
| Actuators | ||
| Gas | Up to 8 MFC’s with solenoid valves or up to 8 rotameters with solenoid valves | |
| Liquids | Up to 4 internal fixed speed pumps | Up to 4 internal variable speed pumps |
| Up to 2 external variable speed pumps | 2+ external variable speed pumps | |
| Stirring | AC or DC motor drive | |
| Temperature | Heating blanket or external Temperature Control Unit (TCU) | |
| TCU options | Thermoflex Neslab, Lauda, GWK, Polyscience | |
| Control | ||
| Control Hardware and Software platform | Applikon proprietary and Applikon Firmware | Siemens or Allen Bradley Siemens, Allen Bradley, iFix, DeltaV |
| Certifications | CE certified, GAMP compliant | |
| 21 CFR part 11 compatible | Yes | Yes |
| Communication & SCADA | Lucullus PIMS, BioXpert W10, DeltaV, iFix | |
| Applikon OPC server availabl | ||
The Applikon SUB-Control is ideal for following applications:
- Microbial and Cell cultivation
- Batch, Fed-Batch, Perfusion and Continuous cultivation
- Single-use bioreactor processes